Arsenal's Robin van Persie is involved in all three goals as the Gunners beat Tottenham 3-0, Portsmouth's Aruna Dindane is also amongst the points with a hat-trick and an assist in the 4-0 win over Wigan.
Each week the Goals Guide will take a look back at the weekend's action, review all the goals and explain any dubious assists. This weekend, Liverpool suffer their fifth defeat, are reduced to nine men and see Chelsea, United and Arsenal win big.
Portsmouth striker Aruna Dindane was the top points scorer this weekend. The Ivory Coast international bagged a hat-trick and an assist worth 11 points as Pompey recorded their first home win of the season by crushing Wigan 4-0.
Team news ahead of Fulham v Liverpool at Craven Cottage. Davies could return for Fulham, but Murphy is still out. Gerrard is unlikely to feature for Liverpool , Johnson is out, and new-boy Aquilani has a virus.
Team news ahead of Stoke v Wolves at the Britannia. Sorensen returns for Stoke after missing the Spurs win, but Huth is still suspended. Ebanks-Blake and Doyle should continue in attack for Wolves.
Team news ahead of Sunderland v West Ham at the Stadium of Light. Darren Bent set to play for the Black Cats despite a knee injury scare but Scott Parker is suspended for the Hammers.
Team news ahead of the North London derby between Arsenal and Tottenham. Spurs have several key players out and who will start in goal for the Gunners?
Team news ahead of the clash of the cities with Birmingham and Manchester locking horns at St Andrews. Joe Hart will be missing for Birmingham, while the away side should welcome the return of defender Kolo Toure.
Team news ahead of Burnley's clash with Hull City on Saturday. Both sides have injury concerns over thier first choice keepers with Boaz Myhill missing for Hull and Brian Jensen facing a late fitness test for the Clarets.
Team news ahead of Bolton v Chelsea at the Reebox. Bolton will name their first choice team after resting several key players when the two clubs met in the League Cup on Wednesday. Chelsea won 4-0 and will restore Drogba and Anelka to the front-line.
Team news ahead of Portsmouth's clash with Wigan at Fratton Park. The home side will atempt to lift themselves away from the foot of the table without Diop and Hreidarsson, while Wigan will be missing Honduran full-back Maynor Figueroa.
Team news ahead of Manchester United v Blackburn at Old Trafford. Vidic and Ferdinand are both major doubts for Manchester United and Giggs could also miss out. Di Santo returns for Blackburn after sitting out the heavy Chelsea defeat.