Arsenal midfielder Aaron Ramsey has been ruled out for another six weeks following a recurrence of his thigh injury. Leaders Manchester City are expected to be without Sergio Aguero when they take on title rivals Chelsea on Monday night.
The January Transfer Window is closing fast and Premier League managers have been desperately searching for new strikers to improve their chances in the battles for survival, Europe and the title.
Liverpool crushed local rivals Everton 4-0 in the Merseyside derby on Tuesday night and Daniel Sturridge scored two goals worth six points. The England international calmly found the back of the net twice in two minutes.
Juan Mata could make his debut for Manchester United when they host Cardiff at Old Trafford on Tuesday night after completing his £37.1m move from Chelsea. The silky Spaniard may even be joined in the starting 11 by Robin van Persie and Wayne Rooney.
Buccaneering full-back Seamus Coleman will miss Everton's FA Cup trip to Stevenage with a hamstring injury but should return for Tuesday's Merseyside derby. The Irishman has been a popular fantasy football selection this season.
The January Transfer Window really sparked into life over the past few days with the rumoured sale of Juan Mata to Manchester United. The Insider Eye takes another look at the latest movers and assumes the £37m deal will go through.
There weren't many Fantasy League points on offer as West Brom and Everton played out a tight 1-1 draw at the Hawthorns on Monday night. The visitors took the lead through Kevin Mirallas in Pepe Mel's first game in charge.
Chelsea striker Samuel Eto'o was the top scoring player at the weekend with nine points after leading the Blues to victory over Manchester United.
Skilful striker Sergio Aguero is available for Manchester City after his injury absence and could go straight into the starting 11 that faces Cardiff. The Argentina international has already plundered 13 league goals this season despite missing a month with a calf problem.
The Player List has been updated with the latest additions. Who will you sign? After a slow start the January Transfer Window has begun to gather some momentum. The Insider Eye has taken a look at the week's new arrivals.
Industrious playmaker Jack Wilshere inspired Arsenal to victory at Aston Villa on Monday night and walked away with five points. The Englishman opened the scoring and recorded an assist.
Wing wizard Adam Johnson was the top scoring player at the weekend with a sensational 11 points from Sunderland's emphatic 4-1 win over Fulham.