Each week the Goals Guide will take a look back at the weekend's action, review all the goals and explain any dubious assists.
Chelsea succumbed to their first defeat under Carlo Ancelotti as a superb Wigan side ran out 3-1 winners, and picked up their first win over one of the 'big four' in 35 attempts.
Titus Bramble opened the scoring from close range when he headed in Charles N'Zogbia's corner before Didier Drogba levelled with a scuffed shot after being found by Florent Malouda.
Hugo Rodallega fired Chelsea in front from the spot after being fouled by Petr Cech, who was subsequently sent off.
As it was Rodallega who was fouled and then scored the kick himself, no assist is given.
Goalkeepers and defenders receiving red cards can lose points after they are sent off, so if a player is sent off and his team concedes goals after his dismissal, he continues to lose the points that his team-mates do.
In Cech's case he got sent off after 51 minutes and so scores 1 ‘defender game played’ point for playing 45 minutes, but then -3 for Chelsea conceding 3 goals making a score of -2 points in total for the match.
As ten-man Chelsea pushed for an equaliser, Wigan caught them on the break and Maynor Figueroa slid the ball across goal leaving Paul Scharner with a simple tap-in.
Chelsea actually finished the game with nine men as Ashley Cole was forced off injured shortly before the third Wigan goal, but he could not be replaced as they had used all three of their substitutes.
Therefore Cole effectively still deemed as being 'in play' when the third Wigan goal went in, and so could he could have come back on at any point after receiving treatment, meaning he still scores -2 for the game because he was not actually substituted off.
Manchester United took advantage of Chelsea's slip-up and moved to the top of the table with a 2-0 win away at Stoke.
Ryan Giggs was again the star of the show, coming off the bench to setup both goals, the first for Dimitar Berbatov who had a simple tap-in and the second for John O'Shea to head home.
Free-scoring Liverpool are hot on their heels though and demolished struggling Hull 6-1 at Anfield thanks to a wonderful Fernando Torres hat-trick.
Some excellent footwork enabled the Spaniard to open the scoring after receiving a pass from Albert Riera before Geovanni latched onto a loose ball and fired in the leveller.
Torres rounded the keeper to restore the lead before embarrassing the defence to complete his hat-trick, thanks to great work from Yossi Benayoun on both occasions.
Steven Gerrard received a short pass from Emiliano Insua before beating everyone with his cross-shot which found the top corner of the net.
Ryan Babel came off the bench to complete the scoring with a brace, firstly tapping Dirk Kuyt's cross and then inadvertently deflecting in Riera's shot.
Robbie Keane bagged four goals as Tottenham also went goal crazy, beating Burnley 5-0 and moving into the top four.
Keane opened the scoring from the spot after Jermain Defoe had been fouled before Jermaine Jenas fired in a second following an attempted Burnley clearance.
Keane bagged his second with 15 minutes left, firing into the top corner after a pass from Aaron Lennon before smashing in his hat-trick after receiving the ball from Tom Huddlestone.
He completed the rout with the help of the post after being picked out by Peter Crouch.
Arsenal moved above Aston Villa and Manchester City with a 1-0 win at Fulham on Saturday tea time, Robin van Persie bagging the only goal of the game from Cesc Fabregas' pass.
Villa slipped up due to a dubious penalty decision that allowed Blackburn to grab a last-gasp winner despite taking the lead through Gabriel Agbonlahor after James Milner had flicked on Brad Friedel's goal-kick.
Because Milner's flick didn't change the direction of Friedel's kick a double assist was given.
Christopher Samba levelled matters when Villa failed to clear Ryan Nelsen's long punt through the middle and then David Dunn won it from the spot late-on after Richard Dunne handled.
Because Dunne's hand-ball was not on the goal-line and he was not subsequently sent off, no assist was given.
Sunderland were also amongst the goals as they ran out 5-2 winners over Wolves in Sunday's game.
Darren Bent opened the scoring after nine minutes after being felled in the box and converting the kick himself, before being fouled again only to hand the ball to Kenwyne Jones to score the second from the spot after the break.
Sunderland had a two goal cushion for just two minutes though after Christophe Berra's shot was parried straight into the unfortunate John Mensah and the ball bounced into his own net.
Goalkeeper parries do no remove assists and so Berra gets the two Fantasy League points for his initial effort.
Five minutes later the visitors had parity, Kevin Doyle the quickest to react when a close-range indirect free-kick rebounded off the wall in his direction.
Jones restored Sunderland's lead with an excellent low drive after receiving the ball from Bent
before Michael Turner rose unmarked to head in Andy Reid's cross.
Michael Mancienne unluckily deflected Bent's low drive into his own net to complete the scoring late-on.
Portsmouth remain rooted to the bottom of the table as Johnny Heitinga's long-ball found Louis Saha who slotted in the only goal of the game to give Everton a 1-0 win.
Finally, Bolton scored late-on again but this time secured all three points in a 2-1 win at Birmingham.
Tamir Cohen kept up his excellent recent form heading in after Sam Ricketts' long throw-in was flicked on by Kevin Davies.
Davies' flick did not change the direction of Ricketts' throw and so a double assist was given.
Kevin Phillips levelled six minutes from time, firing in a low shot after a pass from Christian Benitez before Chung-Young Lee tapped in after Matthew Taylor's free-kick came back off the post.
Shots that hit the woodwork do not remove assists and so Taylor gets the two Fantasy League points for his initial effort.