England international Rickie Lambert was the top scoring player at the weekend with seven points following Southampton's stylish 3-0 win at Fulham. The target-man was involved all three Saints goals.
Arsenal midfielder Aaron Ramsey has been ruled out for another six weeks following a recurrence of his thigh injury. Leaders Manchester City are expected to be without Sergio Aguero when they take on title rivals Chelsea on Monday night.
Liverpool crushed local rivals Everton 4-0 in the Merseyside derby on Tuesday night and Daniel Sturridge scored two goals worth six points. The England international calmly found the back of the net twice in two minutes.
Juan Mata could make his debut for Manchester United when they host Cardiff at Old Trafford on Tuesday night after completing his £37.1m move from Chelsea. The silky Spaniard may even be joined in the starting 11 by Robin van Persie and Wayne Rooney.
Manchester City kept their quadruple dreams alive by launching an extraordinary comeback at home to Watford in the FA Cup Fourth Round and Sergio Aguero scored nine points. The prolific front-man bagged a second half hat-trick.
Buccaneering full-back Seamus Coleman will miss Everton's FA Cup trip to Stevenage with a hamstring injury but should return for Tuesday's Merseyside derby. The Irishman has been a popular fantasy football selection this season.
Chelsea striker Samuel Eto'o was the top scoring player at the weekend with nine points after leading the Blues to victory over Manchester United.
Skilful striker Sergio Aguero is available for Manchester City after his injury absence and could go straight into the starting 11 that faces Cardiff. The Argentina international has already plundered 13 league goals this season despite missing a month with a calf problem.
Industrious playmaker Jack Wilshere inspired Arsenal to victory at Aston Villa on Monday night and walked away with five points. The Englishman opened the scoring and recorded an assist.
Midfield powerhouse Yaya Toure is a doubt for Manchester City's trip to Newcastle on Sunday. The Ivorian international suffered an ankle injury in midweek.
Newcastle will be without two first choice defenders when they take on Cardiff and their new manager Ole Gunnar Solskjaer. Meanwhile, Mesut Ozil could return from a shoulder injury for Arsenal to face North London rivals Tottenham.
Supersub Oscar started the New Year in the best possible fashion by topping the Fantasy League points charts after inspiring Chelsea to victory at Southampton. The Brazilian playmaker had a part in all three goals