Sunday's Manchester derby takes centre stage, but there are plenty of other massive games at both ends of the table this weekend.
Fantasy League managers rocked by news of Leighton Baines injury. The Everton full-back is a popular performer, but could miss this weekend's trip to Manchester City because of a hamstring problem. All this and more in today's injury round-up.
The wonders of a double Game Week. If it only feels like yesterday that you were checking your Fantasy League teams for your latest points, that's because it was. On to the weekend!
We take a look back at how points and assists were dished out last night. Wayne Routledge rocketed to six points, while Steven Gerrard and Jose Fonte collected assists that will provoke discussion.
Team news for Southampton's clash with Norwich City on Saturday.
Each Monday morning during the season, we will look back over the weekend's action and explain any assists that may not be immediately obvious. This should be your first port of call on a Monday morning. If you don't understand an assist that is not listed here then drop us an email.
After the highs and mostly lows, for English clubs anyway, of the Champions League, it's back to domestic matters, culminating in a top of the table clash between two European drop-outs.
Find out who topped the Professional and Classic weekly standings for game week 14, and the 11 players who make it into the Team of the Week.
Full-back Jose Enrique picked up a Fantasy League grand slam, a goal, an assist and a clean sheet, for eight points as Liverpool beat Wigan 3-0 on Saturday. Man City striker Carlos Tevez also scored eight points against Villa.
The Insider Eye is back to preview every Premier League game, including: A North London derby, the bottom two go head-to-head and a clash between the Premier League best defences.